Signal detection:
Signal detection involves a range of techniques. The WHO defines a safety signal as: "Reported information on a possible causal connection between an adverse event and a drug, the relationship being unknown or incompletely documented previously". Commonly more than a single report is required to generate a signal, depending upon the event and quality of the information available.
Data mining pharmacovigilance databases is one approach that has become increasingly popular with the availability of extensive data sources and low-cost computing resources. The data sources may be owned by a pharmaceutical company, a drug regulatory authority, or a large healthcare provider. Individual Case Safety Reports (ICSRs) in these databases are retrieved and converted into structured format, and statistical methods (usually a mathematical algorithm) are applied to calculate statistical measures of association. If the statistical measure crosses an arbitrarily set threshold, a signal is declared for a given drug associated with a given adverse event. All signals deemed worthy of exploration, require further analysis using all available data in an attempt to confirm or refute the signal. If the analysis is inconclusive, extra data may be needed such as a post-marketing observational trial.
- Individual Case Review
- Non Clinical Studies
- Aggregate analysis
- Periodic Reports
Related Conference of Signal detection:
July 21-22, 2025
11th International Conference on Antimicrobials & Antibiotic Resistance
Vancouver, Canada
August 25-26, 2025
11th International Conference on Pharmaceutical Regulatory Affairs and IPR
Vancouver, Canada
September 08-09, 2025
26th International Conference and Exhibition on Pharmaceutics & Novel Drug Delivery Systems
Frankfurt, Germany
September 08-09, 2025
13th International Conference and Exhibition on Natural Products and Medicinal Plants Research
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September 15-16, 2025
42nd International Conference on Drug Discovery and Drug delivery system
Paris, France
September 22-23, 2025
20th International Conference on Pharmaceutical Formulations & Drug Delivery
Toronto, Canada
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10th International Conference on Future Pharma and Innovations
Amsterdam, Netherlands
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6th Annual Congress on Antibiotics and Bacterial Infections
Amsterdam, Netherlands
November 13-14, 2025
28th International Conference and Exhibition on Pharmaceutical Formulations
Paris, France
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21st International Conference on Pharmaceutical Chemistry
Aix-en-Provence, France
November 25-26, 2025
4th World Congress on Medicinal Chemistry and Computer Aided Drug Design
Aix-en-Provence, France
November 27-28, 2025
4th World Conference on Pharma Industry and Medical Devices
Zurich, Switzerland
December 15-16, 2025
3rd International Conference on Current Advances In Pharmaceutical Industry And development
Amsterdam, Netherlands
January 28-29, 2026
23rd International Pharmaceutical Sciences & Life Saving Drugs
Bangkok, Thailand
June 08-09, 2026
25th International Conference on Medicinal and Pharmaceutical Chemistry
San Diego, USA
June 08-09, 2026
8th International Conference and Exhibition on Pharmaceutical Development and Technology
San Diego, USA
Signal detection: Conference Speakers
Recommended Sessions
- Adverse Drug Reactions:
- Case Report Form in Clinical Trials:
- Data Quality Management & Analysis:
- Drug Safety:
- Evaluation & Prevalence of Pharmacovigilance:
- Pharmacology & Drug Development:
- Pharmacovigilance Risk Management:
- Prevalence of Potential Drug- Drug Interaction:
- Regulatory Affairs:
- Signal detection:
- Vaccines and biological medicines:
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