Signal detection:
Signal detection involves a range of techniques. The WHO defines a safety signal as: "Reported information on a possible causal connection between an adverse event and a drug, the relationship being unknown or incompletely documented previously". Commonly more than a single report is required to generate a signal, depending upon the event and quality of the information available.
Data mining pharmacovigilance databases is one approach that has become increasingly popular with the availability of extensive data sources and low-cost computing resources. The data sources may be owned by a pharmaceutical company, a drug regulatory authority, or a large healthcare provider. Individual Case Safety Reports (ICSRs) in these databases are retrieved and converted into structured format, and statistical methods (usually a mathematical algorithm) are applied to calculate statistical measures of association. If the statistical measure crosses an arbitrarily set threshold, a signal is declared for a given drug associated with a given adverse event. All signals deemed worthy of exploration, require further analysis using all available data in an attempt to confirm or refute the signal. If the analysis is inconclusive, extra data may be needed such as a post-marketing observational trial.
- Aggregate analysis
- Individual Case Review
- Non Clinical Studies
- Periodic Reports
Related Conference of Signal detection:
November 19-20, 2026
14th International Conference and Exhibition on Natural Products and Medicinal Plants Research
Dubai, UAE
November 26-27, 2026
5th World Conference on Pharma Industry and Medical Devices
Zurich, Switzerland
December 14-15, 2026
5th International Conference and Expo on Pharmaceutics & Novel Drug Delivery Systems
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15th International Conference on Clinical Research & Clinical Trials
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18th International Conference on Pharmaceutical Education and Practice
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9th International Conference on Pharmaceutical Research
&
Innovations in Pharma Industry
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April 01-02, 2027
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Madrid, Spain
April 29-30, 2027
26th International Conference on Medicinal and Pharmaceutical Chemistry
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April 29-30, 2027
9th International Conference and Exhibition on Pharmaceutical Development and Technology
Geneva, Switzerland
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21st International Conference on Pharmaceutical Formulations & Drug Delivery
Tokyo, Japan
Signal detection: Conference Speakers
Recommended Sessions
- Adverse Drug Reactions:
- Case Report Form in Clinical Trials:
- Data Quality Management & Analysis:
- Drug Safety:
- Evaluation & Prevalence of Pharmacovigilance:
- Pharmacology & Drug Development:
- Pharmacovigilance Risk Management:
- Prevalence of Potential Drug- Drug Interaction:
- Regulatory Affairs:
- Signal detection:
- Vaccines and biological medicines:
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- Pharmacovigilance and Drug Safety Monitoring - Generic Drugs 2026 (UK)
- Pharmacovigilance in Clinical Trials - Clinical Trials Congress-2026 (France)
- Pharmacy Practice - Pharmaceuticals-2027 (France)
- Phases of Clinical Trials - Clinical Trials Congress-2026 (France)
- Phytochemicals in Drug Discovery - PHARAMACEUTICAL CONF 2026 (France)
- Phytochemistry - Naturalproducts 2026 (UAE)
- Placebo-Controlled Studies - Clinical Trials Congress-2026 (France)
- Polymer & Material Chemistry - PHARAMACEUTICAL CONF 2026 (France)
- Population Health - Personalizedmedicine-2026 (Switzerland)
- Post-Marketing Surveillance and Phase IV Trials - Clinical Trials Congress-2026 (France)
- Precision Medicine - Personalizedmedicine-2026 (Switzerland)
- Precision Medicine and Biomarker Discovery - Clinical Trials Congress-2026 (France)
- Precision-Driven Chemical Innovation in Drug Development - PHARAMACEUTICAL CONF 2026 (France)
- Process Chemistry and Pharmaceutical Manufacturing - PHARMACEUTICAL CHEMISTRY 2027 (Italy)
- Public Health and Pharmaceutical Policy - PHARMA CONFERENCE 2026 (Spain)
- Pulmonary Hypertension and Targeted Therapies - Cardiovascular-2027 (France)
- QC & QA: Quality control and Quality assurance - MedTech-2026 (Switzerland)
- Quality Assurance (QA) in Clinical Trials - Clinical Trials Congress-2026 (France)
- Quality Assurance and Quality Control in Pharmaceutical Industries - Drug Safety 2026 (Italy)
- Quality Assurance, GMP & Biotech Manufacturing Excellence - PHARMA BIOTECH 2026 (UK)
- Quality by design (QbD) approach - MedTech-2026 (Switzerland)
- Quality Control and Analytical Method Development - Generic Drugs 2026 (UK)
- Quality Control and Regulatory Considerations in Drug Delivery Systems - Pharmaceutica-2026 (Netherlands)
- Quantitative Systems Pharmacology and Computational Modeling - Generic Drugs 2026 (UK)
- Quantum Chemistry in Drug Design - PHARAMACEUTICAL CONF 2026 (France)
- Radiopharmaceutical Chemistry - PHARAMACEUTICAL CONF 2026 (France)
- Radiopharmaceuticals - Pharmaceuticals-2027 (France)
- Randomization in Trials - Clinical Trials Congress-2026 (France)
- Real-World Evidence (RWE) and Real-World Data (RWD) - Clinical Trials Congress-2026 (France)
- Real-World Evidence, Decentralized Trials & Emerging Technologies - EURO CLINICAL TRIALS 2026 (UK)
- Recent Innovations in Pharmaceutical Technology - Clinical Trials Congress-2026 (France)
- Regenerative Medicine & Stem Cell Clinical Trials - EURO CLINICAL TRIALS 2026 (UK)
- Regenerative Medicine and Cardiovascular Therapeutics - Cardiovascular-2027 (France)
- Regulatory Affairs & Global Compliance in Clinical Trials - EURO CLINICAL TRIALS 2026 (UK)
- Regulatory Affairs & Pharmaceutical Policy - PHARMA EDUCATION 2027 (Italy)
- Regulatory Affairs and Drug Approval Systems - PHARMA CONFERENCE 2026 (Spain)
- Regulatory Affairs and Quality Assurance - Drug-Delivery-2026 (France)
- Regulatory Affairs and Quality Assurance in Pharmaceutics - Pharmaceutica-2026 (Netherlands)
- Regulatory Affairs, Quality Compliance, and Intellectual Property - PHARMACEUTICAL CHEMISTRY 2027 (Italy)
- Regulatory Authority Compliance - MedTech-2026 (Switzerland)
- Regulatory Compliance and Ethics - Clinical Trials Congress-2026 (France)
- Regulatory Frameworks and Global Guidelines for Generic Medicines - Generic Drugs 2026 (UK)
- Regulatory Guidelines and Global Compliance in Pharmaceuticals - Drug Safety 2026 (Italy)
- Regulatory Pharmacology and Toxicology - Euro Pharmacology 2027 (France)
- Regulatory Science, Manufacturing & Scale-Up of Drug Delivery Systems - Drug Delivery 2027 (Austria)
- Regulatory, Quality Control, and Translational Aspects - Drug Devilvery 2027 (France)
- Reproductive and Developmental Toxicology - Euro Pharmacology 2027 (France)
- Risk Assessment and Safety Evaluation in Drug Development - Drug Safety 2026 (Italy)
- Risk-Based Monitoring (RBM) - Clinical Trials Congress-2026 (France)
- Role of Digital Health and AI in Generic Drug Industry - Generic Drugs 2026 (UK)
- Site Selection and Management - Clinical Trials Congress-2026 (France)
- Smart Polymers and Biomaterials - Drug-Delivery-2026 (France)
- Smart Polymers for Drug Delivery - Pharmaceutica-2026 (Netherlands)
- Smart, Stimuli-Responsive & Intelligent Drug Delivery - Drug Delivery 2027 (Austria)
- Stereochemical Drug Design - PHARAMACEUTICAL CONF 2026 (France)
- Supply Chain and Distribution of Generic Medicines - Generic Drugs 2026 (UK)
- Supply Chain Management - Pharmaceuticals-2027 (France)
- Supply Chain Management - Pharmaceuticals-2027 (France)
- Targeted & Precision Drug Delivery - Drug Delivery 2027 (Austria)
- Targeted Oral and Gastro-Resistant Formulations - Drug Devilvery 2027 (France)
- Targeted Therapies - Personalizedmedicine-2026 (Switzerland)
- Technology in Pharma Sciences - MedTech-2026 (Switzerland)
- Telemedicine - Personalizedmedicine-2026 (Switzerland)
- Theranostics and Personalized Medicine - Drug Devilvery 2027 (France)
- Toxicology and Risk Assessment - Euro Pharmacology 2027 (France)
- Track 10. Pharmacovigilance - Pharma Expo-2027 (France)
- Track 6. Pharmacology - Pharma Expo-2027 (France)
- Track 8. Clinical Research . - Pharma Expo-2027 (France)
- Track 10:Digital Health - Clinical Trials-2027 (UK)
- Track 11. Pharmaceutics - Pharma Expo-2027 (France)
- Track 11: Artificial Intelligence - Clinical Trials-2027 (UK)
- Track 12. Pharmacogenomics - Pharma Expo-2027 (France)
- Track 12:Clinical Data - Clinical Trials-2027 (UK)
- Track 13. Bioinformatics - Pharma Expo-2027 (France)
- Track 13: Patient Safety - Clinical Trials-2027 (UK)
- Track 14. Immunotherapy - Pharma Expo-2027 (France)
- Track 14: Safety Surveillance - Clinical Trials-2027 (UK)
- Track 15. Herbal Medicine - Pharma Expo-2027 (France)
- Track 15: Regulatory Compliance - Clinical Trials-2027 (UK)
- Track 1: Pharmacovigilance - Clinical Trials-2027 (UK)
- Track 2: Clinical Trials - Clinical Trials-2027 (UK)
- Track 2: Medicinal Chemistry - Pharma Expo-2027 (France)
- Track 3: Drug Delivery - Pharma Expo-2027 (France)
- Track 3: Drug Safety - Clinical Trials-2027 (UK)
- Track 4 :Nanomedicine - Pharma Expo-2027 (France)
- Track 4: Risk Management - Clinical Trials-2027 (UK)
- Track 5: Biotechnology - Pharma Expo-2027 (France)
- Track 5: Signal Detection - Clinical Trials-2027 (UK)
- Track 6: Clinical Research - Clinical Trials-2027 (UK)
- Track 7. Toxicology - Pharma Expo-2027 (France)
- Track 7:Regulatory Affairs - Clinical Trials-2027 (UK)
- Track 8:Real-World Evidence - Clinical Trials-2027 (UK)
- Track 9. Pharmacokinetics - Pharma Expo-2027 (France)
- Track 9: Safety Analytics - Clinical Trials-2027 (UK)
- Track :1 Drug Discovery - Pharma Expo-2027 (France)
- Transdermal and Intradermal Delivery Systems - Drug-Delivery-2026 (France)
- Transdermal and Topical Drug Delivery - Drug Devilvery 2027 (France)
- Translational Research - Personalizedmedicine-2026 (Switzerland)
- Vaccine Delivery Systems - Pharmaceutica-2026 (Netherlands)
- Vaccine Delivery Technologies - Drug-Delivery-2026 (France)
- Vaccine Development and Immunopharmacology - Drug Safety 2026 (Italy)
- Vaccine Technologies & Immunotherapeutics - PHARMA BIOTECH 2026 (UK)
- Vaccines as a Strategy to Combat AMR - Antibiotics Resistance 2027 (Spain)
- Vascular Pharmacology and Endothelial Function - Cardiovascular-2027 (France)
- Wearable and Implantable Drug Delivery Devices - Drug Devilvery 2027 (France)